Role of tripeptidyl peptidase II in the processing of Listeria monocytogenes-derived MHC class I-presented antigenic peptides.

作者: Silke Grauling-Halama , Udo Bahr , Simone Schenk , Gernot Geginat

DOI: 10.1016/J.MICINF.2009.04.019

关键词: EpitopeProtease inhibitor (biology)ProteasomeBacterial antigenTripeptidyl peptidase IICytotoxic T cellMHC class IBiologyAntigen presentationMicrobiology

摘要: … inhibitors of the proteasome alone. Further analysis revealed that inhibitors of the cytoplasmic tripeptidyl peptidase … simultaneous inhibition of the proteasome and tripeptidyl peptidase II, …

参考文章(22)
Rickard Glas, Matthew Bogyo, John S. McMaster, Maria Gaczynska, Hidde L. Ploegh, A proteolytic system that compensates for loss of proteasome function Nature. ,vol. 392, pp. 618- 622 ,(1998) , 10.1038/33443
Lars Stoltze, Markus Schirle, Gerold Schwarz, Christian Schröter, Michael W. Thompson, Louis B. Hersh, Hubert Kalbacher, Stefan Stevanovic, Hans-Georg Rammensee, Hansjörg Schild, Two new proteases in the MHC class I processing pathway Nature Immunology. ,vol. 1, pp. 413- 418 ,(2000) , 10.1038/80852
E. John Wherry, Tatiana N. Golovina, Susan E. Morrison, Gomathinayagam Sinnathamby, Michael J. McElhaugh, David C. Shockey, Laurence C. Eisenlohr, Re-evaluating the generation of a "proteasome-independent" MHC class I-restricted CD8 T cell epitope. Journal of Immunology. ,vol. 176, pp. 2249- 2261 ,(2006) , 10.4049/JIMMUNOL.176.4.2249
Ulrike Seifert, Concepción Marañón, Ayelet Shmueli, Jean-François Desoutter, Lisa Wesoloski, Katharina Janek, Peter Henklein, Susanne Diescher, Muriel Andrieu, Henri de la Salle, Toni Weinschenk, Hansjörg Schild, Diego Laderach, Anne Galy, Gaby Haas, Peter-M. Kloetzel, Yuval Reiss, Anne Hosmalin, An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope. Nature Immunology. ,vol. 4, pp. 375- 379 ,(2003) , 10.1038/NI905
E. Geier, G. Pfeifer, M. Wilm, M. Lucchiari-Hartz, W. Baumeister, K. Eichmann, G. Niedermann, A Giant Protease with Potential to Substitute for Some Functions of the Proteasome Science. ,vol. 283, pp. 978- 981 ,(1999) , 10.1126/SCIENCE.283.5404.978
Peter van Endert, Role of tripeptidyl peptidase II in MHC class I antigen processing – the end of controversies? European Journal of Immunology. ,vol. 38, pp. 609- 613 ,(2008) , 10.1002/EJI.200838181
Merceditas S. Villanueva, Philip Fischer, Kevin Feen, Eric G. Pamer, Efficiency of MHC class I antigen processing: A quantitative analysis Immunity. ,vol. 1, pp. 479- 489 ,(1994) , 10.1016/1074-7613(94)90090-6
Tomo Saric, Jochen Beninga, Claudia I. Graef, Tatos N. Akopian, Kenneth L. Rock, Alfred L. Goldberg, Major Histocompatibility Complex Class I-presented Antigenic Peptides Are Degraded in Cytosolic Extracts Primarily by Thimet Oligopeptidase Journal of Biological Chemistry. ,vol. 276, pp. 36474- 36481 ,(2001) , 10.1074/JBC.M105517200
Jonathan W Yewdell, Jack R Bennink, Cut and trim: generating MHC class I peptide ligands Current Opinion in Immunology. ,vol. 13, pp. 13- 18 ,(2001) , 10.1016/S0952-7915(00)00175-8