Electrospun nanofibers as a wound dressing for treating diabetic foot ulcer.

摘要: Diabetes is one of the most prevalent diseases in world with high-mortality and complex complications including diabetic foot ulcer (DFU). It has been reported that difficulties repairing wound related to DFU much relationship infection, change inflammatory responses, lack extracellular matrix (ECM), failure angiogenesis. Following development medical materials pharmaceutical technology, nanofibers developed by electrospinning huge porosity, excellent humidity absorption, a better oxygen exchange rate, some antibacterial activities. That say, as potential material, must be wonderful candidate for treatment so many benefits. Careful selection polymers from natural resource synthetic can widen nanofibrous application. Popular methods applied fabrication consist uniaxial coaxial electrospinning. Furthermore, loading chemical, biochemical active ingredient (API) or even stem cells dosage forms DFU. This review summarizes present techniques dressing (ND) utilizes variety agents offer health care patients suffering