Catabolism of unnatural carbohydrates by micro-organisms.

摘要: Publisher Summary The chapter focuses on the extensive investigations into metabolism of unnatural carbohydrates by microorganism. A number microbial cultures for ability to ferment rare five-carbon sugars are tested. In tests with fermentation media, this strain was able metabolize all eight aldopentose structures (D- and L-ribose, D- L-arabinose, L-xylose L-lyxose) four pentitol (ribitol, L-arabitol, xylitol). This seemed remarkable because only three aldopentoses (D-ribose, L-arabinose D-xylose) two pentitols (ribitol D-arabitol) were considered be available as growth substrates in nature. versatility organism its utilize these sources carbon energy is discussed chapter. possible exception which not testing a potential substrate. It has been recognized laboratories that studies mechanisms micro-organisms novel may lead increased understanding events, result evolution catabolic pathways microorganisms. spite facts L-arabitol degraded through common intermediate ribitol dehydrogenase required catalyse first step degradation cells constitutive maintain high levels enzyme during L-arabitol. relatively poor activity oxidation substrate results slow decreased accumulation metabolic intermediates high-energy compounds, could repression pathway enzymes.