Identification of group-common linear epitopes in structural and nonstructural proteins of enteroviruses by using synthetic peptides.
作者： J Cello , A Samuelson , P Stålhandske , B Svennerholm , S Jeansson
DOI: 10.1128/JCM.31.4.911-916.1993
关键词: Virology 、 Serology 、 Antigenicity 、 Virus 、 Immunoglobulin G 、 Biology 、 Antibody 、 Peptide 、 Enterovirus 、 Epitope
摘要: Synthetic peptides were employed in enzyme-linked immunosorbent assays to identify group-common linear epitopes the structural and nonstructural proteins of enteroviruses. Nine recognized by using sera from patients with heterotypic immunoglobulin G antibody responses enterovirus infections. The most-reactive derived conserved regions amino-terminal part VP1, whereas representing sequences other as well VP2, VP3, VP4, a region showed no or poor reactivity. These findings may be useful development serological tests for diagnosis infections caused broad range
sci-hub.st 参考文章(13)
Jacoba G. Kapsenberg, Picornaviridae: The Enteroviruses (Polioviruses, Coxsackieviruses, Echoviruses) Springer, New York, NY. pp. 692- 722 ,(1988) , 10.1007/978-1-4612-3900-0_36
H. M. Geysen, T. J. Mason, S. J. Rodda, Peptides as Specific Recognition Devices Springer, Berlin, Heidelberg. pp. 111- 119 ,(1991) , 10.1007/978-3-642-76603-9_13
Marianne Forsgren, Relationship between poliovirus and echovirus 6 antigens. I. Immunization experiments in guinea pigs. Archives of Virology. ,vol. 39, pp. 108- 120 ,(1972) , 10.1007/BF01241534
Jaap M. Middeldorp, Rob H. Meloen, Epitope-mapping on the Epstein-Barr virus major capsid protein using systematic synthesis of overlapping oligopeptides Journal of Virological Methods. ,vol. 21, pp. 147- 159 ,(1988) , 10.1016/0166-0934(88)90061-4
Einar G. Torfason, Gun Frisk, Hans Diderholm, Indirect and reverse radioimmunoassays and their apparent specificities in the detection of antibodies to enteroviruses in human sera Journal of Medical Virology. ,vol. 13, pp. 13- 31 ,(1984) , 10.1002/JMV.1890130103
P. Halonen, L. Rosen, R. J. Huebner, Homologous and heterologous complement fixing antibody in persons infected with ECHO; Coxsackie and poliomyelitis viruses. Experimental Biology and Medicine. ,vol. 101, pp. 236- 241 ,(1959) , 10.3181/00379727-101-24896
H. Mario Geysen, Antigen-antibody interactions at the molecular level: adventures in peptide synthesis Immunology Today. ,vol. 6, pp. 364- 369 ,(1985) , 10.1016/0167-5699(85)90096-9
Marc H.V. Van Regenmortel, Structural and functional approaches to the study of protein antigenicity Immunology Today. ,vol. 10, pp. 266- 272 ,(1989) , 10.1016/0167-5699(89)90140-0
Th. Mertens, Ursula Pika, H.J. Eggers, Cross antigenicity among enteroviruses as revealed by immunoblot technique. Virology. ,vol. 129, pp. 431- 442 ,(1983) , 10.1016/0042-6822(83)90181-2
Sylviane Muller, Serge Plaue, Maurice Couppez, Marc H.V. Van Regenmortel, Comparison of different methods for localizing antigenic regions in histone H2A. Molecular Immunology. ,vol. 23, pp. 593- 601 ,(1986) , 10.1016/0161-5890(86)90095-7