Excessive Refined Carbohydrates and Scarce Micronutrients Intakes Increase Inflammatory Mediators and Insulin Resistance in Prepubertal and Pubertal Obese Children Independently of Obesity

摘要: Background. Low-grade inflammation is the link between obesity and insulin resistance. Because physiologic resistance occurs at puberty, obese pubertal children are higher risk for Excessive diets in refined carbohydrates saturated fats factors resistance, but calcium, magnesium, vitamin-D, omega-3 fatty acids likely protect against Objective. To analyze interactions among dietary fat, carbohydrates, vitamin D, on of a sample prepubertal children. Methods. A 229 from Mexico City was analyzed cross-sectional design. Anthropometric measurements, 24 h recall questionnaires, blood samples were obtained. Serum insulin, glucose, 25-OHD3, C-reactive protein, leptin, adiponectin, erythrocytes measured. Parametric nonparametric statistics used analysis. Results. While mean macronutrients intake excessive, micronutrients deficient . Inflammation determinants central magnesium-deficient diets. Determinants circulating magnesium adiponectin. Conclusions. Magnesium-deficient inflammation, while high factor independently adiposity.