Previous thoracic surgery does not increase peri-operative mortality in pediatric heart-lung transplant recipients.

作者: Sofia Koulouri , Marlyn S. Woo , Monica V. Horn , Winfield J. Wells , Vaughn A. Starnes

DOI: 10.1016/J.HEALUN.2003.08.035

关键词: Packed red blood cellsAnastomosisSurgeryCryoprecipitateFresh frozen plasmaMedicinePerioperativeBlood productCardiothoracic surgeryCardiopulmonary disease

摘要: Abstract Background Heart-lung transplant (HLT) is indicated in select children with end-stage cardiopulmonary disease. We sought to determine whether previous thoracic surgery increases peri-operative morbidity and mortality. Methods Retrospective data were analyzed using unpaired Student's t -test Fisher's exact test. Results are reported as mean ± SD. Peri-operative mortality was defined death at ≤30 days post-transplant. From August 1993 through April 2001, 13 patients (mean age 7.9 5.3 years; 9 girls, 4 boys) underwent HLT our center. Eight of (62%) had 5 (38%) did not. Interval last date 45.5 26.4 months (range 6 79 months). compared who recipients There no significant difference weight (18.6 14.3 vs 36.5 20.7 kg, p = 0.09), (6.5 4.5 10.2 6.1 years, 0.23) or duration intubation (14.1 12.9 17.0 30.3 days, 0.83). caval tracheal anastomotic stenoses either group. blood products transfused ≤48 hours after HLT: packed red cells ( 0.16); fresh frozen plasma 0.13); platelets 0.59), cryoprecipitate 0.27). bypass time (129.3 48.2 160.6 73.9 minutes, 0.39); post-operative diaphragm dysfunction (4 8 0 5, 0.1); re-exploration for bleeding (2 1 1.0); 0.48). Conclusions conclude that does not significantly increase product transfusion,

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