The pigment characteristics and productivity shifting in high cell density culture of Monascus anka mycelia

摘要: Monascus mycelia and pigments are promising sources of food medicine with their potential pharmaceutical values health-improving functions. Using high cell density fermentation spp. to achieve higher mycelium yellow pigment production is worthy be researched. In this study, the characteristics productivity shifting in culture anka GIM 3.592 were investigated. The yield up 39.77 g/L dry weight (DCW), which was achieved by fed-batch feeding medium containing C, N, P trace elements, four times than that conventional batch culture. But total decreased 14.6 %, suggested non-coupled growth. Potential novel accumulated constantly at late stage culture, resulted a shift so became dominant pigments. Citrinin extremely low independent ingredients. This study provided suitable strategy produce functional proportion For first time, it reported Monascus.