Spider and wasp neurotoxins: pharmacological and biochemical aspects

作者: Renê de O Beleboni , Andrea B Pizzo , Andréia CK Fontana , Ruither de OG Carolino , Joaquim Coutinho-Netto

DOI: 10.1016/J.EJPHAR.2004.03.049

关键词: NeurotransmitterAnatomyCarrier proteinNeurotransmissionNeurotoxinSpiderIon channelTransporterReceptorBiochemistryBiology

摘要: Venoms from several arthropods are recognized as useful sources of bioactive substances, such peptides, acylpolyamines, and alkaloids, which show a wide range pharmacological effects on synaptic transmission. In this work, we summarize compile biochemical aspects related to spider wasp neurotoxins. Their inhibitory stimulatory actions ion channels, receptors, transporters involved in mammalian insect neurotransmission considered.

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