Experimental pulmonary embolism with electrically activated autologous blood

摘要: Pulmonary thromboembolism is one of the most frequent causes death in our days. Notwithstanding great efforts made clinical and experimental medicine there has been no success as yet filling existing gaps understanding pathophysiology this disease. The blood electrically activated vitro by direct current reacts like an endogenic thrombogenic substance. On condition that such a substance injected into inferior vena cava, clot introduced pulmonary circulation gives rise to varying degree, each depending on injected. In animal experiment it thus become feasible, under standardized reproducible conditions, produce severe or chronic microembolism with subsequent hypertrophy right ventricle. object contribution demonstration new, easy, effective method for induction embolism, which can be treated thrombolysis.