Prevention of Transmission of Virus Infections by Blood Transfusions and Removal of Virus Infectivity from Clotting Factor Concentrates

作者: R. J. Gerety

DOI: 10.1007/978-1-4613-2631-1_18

关键词: Hepatitis AVirusHepatitis B virusViremiaTransmission (medicine)VirologyHepatitisHepatitis BClotting factorMedicine

摘要: Virus infections are serious complications following blood transfusions or intravenous therapy with clotting factor concentrates. Hepatitis A virus (HAV) is rarely transmitted by and never plasma derivatives. characterized a short viremia which most often coincides clinical illness. In addition neutralizing antibodies to HAV present in all pools from concentrates manufactured (1). Chronic B non-A non-B hepatitis commonly follow acute (5 10% for B, more than 40% perhaps close 100% hepatitis). (HBV) serum levels of infectious up 108/ml (infectious units) while generally the range 102/ml (2,3). Little has been published concerning HTLV III plasma.

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