Involvement of caspase-1 in inflammasomes activation and bacterial clearance in S. aureus-infected osteoblast-like MG-63 cells.

作者: Elma Lima Leite , Arthur Gautron , Martine Deplanche , Aurélie Nicolas , Jordane Ossemond

DOI: 10.1111/CMI.13204

关键词: ProteasesSecretionOsteoblastBiologyStaphylococcus aureusMicrobiologyPathogenCaspase 1Immune systemInflammasome

摘要: … a CASP1 −/− MG-63 cell line using CRISPR-Cas9 gene editing for the investigation of inflammasomes involvement during S. aureus infection in a model of BJI. Despite the fact that …

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