A Computational Framework for Breast Surgery: Application to Breast Conserving Therapy

摘要: If a surgical intervention is needed, early stage breast cancer may lead to three basic surgery choices: breast-sparing followed by radiation therapy, mastectomy, mastectomy with reconstruction surgery. Breast-sparing (breast conservation therapy (BCT)) removes the tumor and margin of surrounding normal tissues. It also known other names: lumpectomy, partial segmental quadrantectomy. Radiation follows lumpectomy eliminate any microscopic cells in remaining tissue. The purpose BCT give women same cure rate they would have if were treated but leave intact, an appearance texture as close possible what had before treatment. Trials for conservative patients affected (I II) demonstrated conclusively that produces disease control survival rates at least equivalent those possibly better long run II [1]. combined therapy. While tissue contain negative margin, radiotherapy insure residual are controlled. Contra-indications generally high probability recurrence, damage from irradiation. cosmesis after might be satisfactory, quality result very sensitive location extent tumor. Further, deformable structure complicated anatomy patient specific. mechanical properties glandular, fatty cancerous quite different, vary one another. Cooper’s ligament plays key role outcome. Strong asymmetry or large size prone anesthetic result. Surgical results depending on time scale. Beside short scale modeling caught model, can expect inflammation, postsurgical radiotherapy, healing dynamic change significantly cosmetic In words biology well.