Whole‐heart coronary magnetic resonance angiography at 3 Tesla in 5 minutes with slow infusion of Gd‐BOPTA, a high‐relaxivity clinical contrast agent

摘要: T(1)-shortening contrast agents have been used to improve the depiction of coronary arteries with breath-hold magnetic resonance angiography (MRA). The spatial resolution and coverage are limited by duration arterial phase media passage. In this study we investigated feasibility acquiring free-breathing, whole-heart MRA during slow infusion (0.3 ml/s) for prolonged blood signal enhancement time. Ultrashort TR (3 ms) parallel data acquisition were allow in approximately 5 min. A newly approved gadolinium (Gd)-based high T(1) relaxivity agent, gadobenate dimeglumine ([Gd-BOPTA](2-)), was performed on a whole-body 3 Tesla (T) system signal-to-noise ratio (SNR). Results from eight volunteers demonstrate that method is capable imaging whole heart 4.5 +/- 0.6 Major well depicted SNR (42.4 12.5) contrast-to-noise (CNR; 27.1 7.6).