The origin and definition of brite versus white and classical brown adipocytes.

作者: Matthias Rosenwald , Christian Wolfrum

DOI: 10.4161/ADIP.26232

关键词: White (mutation)BiologyThermogenesisCold adaptationWhite adipose tissueBrown adipose tissueBrown AdipocytesTransdifferentiationBrite AdipocytesEndocrinologyInternal medicine

摘要: … Thus, as long as we lack any trait differentiating adipocytes capable of white to brown transdifferentiation from those cells that are not capable of undergoing this process, the question …

参考文章(47)
M. A. Lazar, How Now, Brown Fat? Science. ,vol. 321, pp. 1048- 1049 ,(2008) , 10.1126/SCIENCE.1164094
Maria Jimenez, Giorgio Barbatelli, Roberta Allevi, Saverio Cinti, Josiane Seydoux, Jean-Paul Giacobino, Patrick Muzzin, Frédéric Preitner, β3‐Adrenoceptor knockout in C57BL/6J mice depresses the occurrence of brown adipocytes in white fat FEBS Journal. ,vol. 270, pp. 699- 705 ,(2003) , 10.1046/J.1432-1033.2003.03422.X
Aaron M. Cypess, Sanaz Lehman, Gethin Williams, Ilan Tal, Dean Rodman, Allison B. Goldfine, Frank C. Kuo, Edwin L. Palmer, Yu-Hua Tseng, Alessandro Doria, Gerald M. Kolodny, C. Ronald Kahn, Identification and Importance of Brown Adipose Tissue in Adult Humans The New England Journal of Medicine. ,vol. 360, pp. 1509- 1517 ,(2009) , 10.1056/NEJMOA0810780
A. Vitali, I. Murano, M.C. Zingaretti, A. Frontini, D. Ricquier, S. Cinti, The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes Journal of Lipid Research. ,vol. 53, pp. 619- 629 ,(2012) , 10.1194/JLR.M018846
Yun-Hee Lee, Anelia P. Petkova, Emilio P. Mottillo, James G. Granneman, In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding Cell Metabolism. ,vol. 15, pp. 480- 491 ,(2012) , 10.1016/J.CMET.2012.03.009
Matthew S. Rodeheffer, Kıvanç Birsoy, Jeffrey M. Friedman, Identification of White Adipocyte Progenitor Cells In Vivo Cell. ,vol. 135, pp. 240- 249 ,(2008) , 10.1016/J.CELL.2008.09.036
Paul Lee, Francesco S. Celi, Kong Y. Chen, Robert J. Brychta, Joyce D. Linderman, Sheila Smith, Amber Courville, William Dieckmann, Peter Herscovitch, Corina M. Millo, Alan Remaley, Brown Fat Activation Mediates Cold-Induced Thermogenesis in Adult Humans in Response to a Mild Decrease in Ambient Temperature The Journal of Clinical Endocrinology and Metabolism. ,vol. 98, ,(2013) , 10.1210/JC.2012-4213
Wouter D. van Marken Lichtenbelt, Joost W. Vanhommerig, Nanda M. Smulders, Jamie M.A.F.L. Drossaerts, Gerrit J. Kemerink, Nicole D. Bouvy, Patrick Schrauwen, G.J. Jaap Teule, Cold-activated brown adipose tissue in healthy men. The New England Journal of Medicine. ,vol. 360, pp. 1500- 1508 ,(2009) , 10.1056/NEJMOA0808718