Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect

作者: H. Maeda , G.Y. Bharate , J. Daruwalla

DOI: 10.1016/J.EJPB.2008.11.010

关键词: LiposomeTargeted therapyPolymer-drug conjugatesCancerTargeted drug deliveryDrugChemotherapyPharmacologyMedicineDrug delivery

摘要: … Under these circumstances tumor-targeted delivery of anticancer … The drug concentration in tumor compared to that of the … passive targeting for momentary tumor delivery, but it means …

参考文章(119)
J. Franklin, H. Tesch, M.-L. Hansmann, V. Diehl, Lymphocyte predominant Hodgkin's disease: Pathology and clinical implication Annals of Oncology. ,vol. 9, pp. 39- 44 ,(1998) , 10.1093/ANNONC/9.SUPPL_5.S39
Yasuhiro Matsumura, Keishi Maruo, Masami Kimura, Tetsuro Yamamoto, Toshimitsu Konno, Hiroshi Maeda, Kinin-generating cascade in advanced cancer patients and in vitro study. Japanese Journal of Cancer Research. ,vol. 82, pp. 732- 741 ,(1991) , 10.1111/J.1349-7006.1991.TB01910.X
L. Harivardhan Reddy, Drug delivery to tumours: recent strategies Journal of Pharmacy and Pharmacology. ,vol. 57, pp. 1231- 1242 ,(2010) , 10.1211/JPP.57.10.0001
Kevin J. Harrington, Kevin J. Harrington, Sima Mohammadtaghi, Richard G. Vile, Daphne Glass, Paul S. Uster, A. Michael Peters, J. Simon W. Stewart, Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes. Clinical Cancer Research. ,vol. 7, pp. 243- 254 ,(2001)
Makoto Sumitomo, Fumiaki Koizumi, Takako Asano, Akio Horiguchi, Keiichi Ito, Tomohiko Asano, Tadao Kakizoe, Masamichi Hayakawa, Yasuhiro Matsumura, Novel SN-38–Incorporated Polymeric Micelle, NK012, Strongly Suppresses Renal Cancer Progression Cancer Research. ,vol. 68, pp. 1631- 1635 ,(2008) , 10.1158/0008-5472.CAN-07-6532
Pierre Pellegrin, Anne Fernandez, Ned J. C. Lamb, René Bennes, Macromolecular uptake is a spontaneous event during mitosis in cultured fibroblasts: implications for vector-dependent plasmid transfection Molecular Biology of the Cell. ,vol. 13, pp. 570- 578 ,(2002) , 10.1091/MBC.01-06-0280
Ernst Wagner, David Curiel, Matt Cotten, Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis Advanced Drug Delivery Reviews. ,vol. 14, pp. 113- 135 ,(1994) , 10.1016/0169-409X(94)90008-6