Apoptosis inhibition in cancer cells: a novel molecular pathway that involves BAG3 protein.

作者: Alessandra Rosati , Massimo Ammirante , Antonio Gentilella , Anna Basile , Michela Festa

DOI: 10.1016/J.BIOCEL.2007.03.007

关键词: Heat shock proteinProteasomeInhibitor of apoptosis domainBAG3Intrinsic apoptosisCell biologyBiologyNeoplastic cellApoptosome assemblyApoptosis

摘要: … regulate apoptosis, a role is emerging for BAG3, a member of the BAG co-chaperone protein … We favor the hypothesis that BAG3 interferes with the binding of Hsc70/Hsp70 to proteins or …

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