The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS.

作者: Daisy Wing-Sze Wong , Elaine Lai-Han Leung , Kimpton Kam-Ting So , Issan Yee-San Tam , Alan Dart-Loon Sihoe

DOI: 10.1002/CNCR.24181

关键词: ALK Gene RearrangementPathologyCancerChromosome breakageLung cancerKRASFusion geneEML4/ALK Fusion GeneBiologyFusion transcriptCancer research

摘要: BACKGROUND: The echinoderm microtubule‐associated protein‐like 4‐anaplastic lymphoma kinase (EML4‐ALK) fusion gene resulting from the chromosome inversion inv(2)(p21;p23…

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