Taking precautions with ACE inhibitors: A theoretical risk exists in patients with unilateral renal artery stenosis

作者: A Kumar , M Asim , A M Davison

DOI: 10.1136/BMJ.316.7149.1921

关键词: Heart failureIn patientMyocardial infarctionCreatinineMedicineUnilateral diseaseAngiotensin-converting enzymeRenal artery stenosisRenal Artery ObstructionCardiologyInternal medicine

摘要: Angiotensin converting enzyme inhibitors have revolutionised the treatment of congestive heart failure,1 hypertension,2 and diabetic nephropathy.3 After myocardial infarction, with angiotensin decreases incidence life threatening left ventricular failure improves survival.4 Yet, despite appearing to be a panacea for vascular diseases, may present hazard patients unsuspected atherosclerotic renovascular disease,5 size that risk growing. Convention dictates if serum creatinine concentration is unchanged several days after starting an inhibitor there no haemodynamically important renal artery stenosis. But this scenario applies only in bilateral disease: unilateral disease these drugs cause ischaemic damage loss function …

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