Modified Triple Chemotherapy
作者： Ross S. Berkowitz , Donald P. Goldstein
DOI: 10.1007/978-1-4612-4698-5_14
关键词: Folinic acid 、 Methotrexate 、 Regimen 、 Combination chemotherapy 、 Molar pregnancy 、 Internal medicine 、 Oncology 、 Gestational trophoblastic disease 、 Cyclophosphamide 、 Medicine 、 Chemotherapy
摘要: The success in the treatment of gestational trophoblastic disease (GTD) over past three decades has been due large part to development regional centers. concentration numbers patients with a relatively rare led refinement diagnostic techniques and establishment protocols so that today virtually all nonmetastatic low-risk metastatic GTD can expect complete remission single-agent chemotherapy. 1–4The small number resistant chemotherapy high-risk disease, however, require utilizing multiple agents. Various combination regimens have used for these women. In recent years, we employed modified triple protocol which includes methotrexate folinic acid, actinomycin D, cyclophosphamide (MAC III). This chapter reviews response rate toxicity this new regimen.
springer.com
sci-hub.st 参考文章(39)
John Robert Lurain, Bernard Halpern, John I. Brewer, Elizabeth E. Torok, Gestational trophoblastic disease: treatment results at the Brewer Trophoblastic Disease Center. Obstetrics & Gynecology. ,vol. 60, pp. 354- 360 ,(1982)
David M. Gershenson, Patton B. Saul, John J. Kavanagh, Alan N. Gordon, Creighton L. Edwards, Larry J. Copeland, High-risk metastatic gestational trophoblastic disease. Obstetrics & Gynecology. ,vol. 65, pp. 550- 556 ,(1985)
Brewer Ji, Lurain, Treatment of high-risk gestational trophoblastic disease with methotrexate, actinomycin D, and cyclophosphamide chemotherapy. Obstetrics & Gynecology. ,vol. 65, pp. 830- 836 ,(1985)
Ross Stuart Berkowitz, Donald Peter Goldstein, Gestational Trophoblastic Neoplasms: Clinical Principles of Diagnosis and Management ,(1982)
Roy Hertz, John Lewis, M.B. Lipsett, Five years' experience with the chemotherapy of metastatic choriocarcinoma and related trophoblastic tumors in women American Journal of Obstetrics and Gynecology. ,vol. 82, pp. 631- 640 ,(1961) , 10.1016/0002-9378(61)90283-6
Charles B. Hammond, Lynn G. Borchert, Lee Tyrey, William T. Creasman, Roy T. Parker, Treatment of metastatic trophoblastic disease: Good and poor prognosis American Journal of Obstetrics and Gynecology. ,vol. 115, pp. 451- 457 ,(1973) , 10.1016/0002-9378(73)90389-X
John B. Schlaerth, C.Paul Morrow, Amodio D. DePetrillo, Sustained remission of choriocarcinoma with cis-platinum, vinblastine, and bleomycin after failure of conventional combination drug therapy American Journal of Obstetrics and Gynecology. ,vol. 136, pp. 983- 985 ,(1980) , 10.1016/0002-9378(80)90622-5
Judith L. Vaitukaitis, Glenn D. Braunstein, Griff T. Ross, A radioimmunoassay which specifically measures human chorionic gonadotropin in the presence of human luteinizing hormone American Journal of Obstetrics and Gynecology. ,vol. 113, pp. 751- 758 ,(1972) , 10.1016/0002-9378(72)90553-4
Charles B. Hammond, John C. Weed, John L. Currie, The role of operation in the current therapy of gestational trophoblastic disease American Journal of Obstetrics and Gynecology. ,vol. 136, pp. 844- 856 ,(1980) , 10.1016/0002-9378(80)91041-8
Roy Hertz, Griff T. Ross, Leo L. Stolbach, Actinomycin D in the Treatment of Methotrexate-resistant Trophoblastic Disease in Women Cancer Research. ,vol. 22, pp. 1015- 1017 ,(1962)