The role of operation in the current therapy of gestational trophoblastic disease

摘要: Results of therapy 257 patients with gestational trophoblastic disease (GTN), treated at one institution and by the same group physicians (1966 to 1978), are presented. An overall remission rate 92% was achieved: nonmetastatic disease, 139/139 (100%); "good" prognosis metastatic GTN, 55/55 (100%), "poor" 42/63 (66%). Chemotherapy, single- or multi-agent, primary treatment modality but selected were also operation and/or x-ray therapy. Surgical (hysterectomy), performed coincident systemic chemotherapy, shown significantly reduce duration hospitalization amount chemotherapy used achieve remission, regardless whether not metastases present. Delayed surgical excision chemotherapy-resistant foci GTN benefit, though less effective than initial operation. intervention for other diseases complications its quite useful stabilize allow successful be completed. There no problems attributable when wound healing postoperative considered.