The role of surgery in gestational trophoblastic disease.

摘要: Fifty-eight consecutive patients with malignant trophoblastic tumors of gestational origin were treated at the 1st Department Obstetrics and Gynecology University Milan between 1975 1981. Thirty-five (60.3%) combined surgery chemotherapy. Of these, 44.8% had genital surgery, 12% extragenital 5.1% emergency laparotomies. Minor was done to 17.1% patients. Five (20.8%) limited uterus chemotherapy only became drug-resistant, whereas 3 (9%) later developed lung metastases. All are alive without any clinical signs disease. When there metastatic tumors, survival group first submitted a "debulking" operation primary focus 80%, 78.5%. Seven cases required for indications discussed in detail because they measurable HCG. Six these thoracotomies one craniotomy. 6 who underwent thoracotomy (83.4%) complete remission. Chemotherapy remains treatment choice tumors. Nevertheless, our data confirm that some cases, mostly high risk group, eradication cannot be obtained antitumor agents. Adjuvant carefully selected helps save those no longer respond