Reproductive performance of women successfully treated for gestational trophoblastic tumors.
作者： P.A.M. Walden , K.D. Bagshawe
DOI: 10.1016/0002-9378(76)90816-4
关键词: Obstetric history 、 Trophoblastic Tumor 、 Medicine 、 Chemotherapy 、 Methotrexate 、 Treated group 、 Gynecology 、 Incidence (epidemiology) 、 Gestation
摘要: The reproductive performance of 36 women who had been successfully treated for gestational trophoblastic tumors with multiple courses cytotoxic agents including methotrexate, 6-mercaptopurine, actinomycin D, and 6-azauridine, between 1962 1972, has studied in comparison patients spontaneously aborted a hydatidiform mole but received no treatment control group consisting attending an antenatal clinic. majority wanted further pregnancies following chemotherapy one or more successful conceptions. incidence abnormal the was higher than that group. Similarly, there number untreated when compared This suggests develop tend to have poor obstetric history this is not significantly worsened by chemotherapy.
sci-hub.se 参考文章(17)
Henry L. Freedman, Antonio Magagnini, Morris Glass, Pregnancies following chemically treated choriocarcinoma. American Journal of Obstetrics and Gynecology. ,vol. 83, pp. 1637- 1641 ,(1962) , 10.1016/0002-9378(62)90182-5
Chemical mutagenesis in mammals and man. Chemical mutagenesis in mammals and man.. ,(1970) , 10.1007/978-3-642-85874-1
David H. Carr, Chromosome anomalies as a cause of spontaneous abortion American Journal of Obstetrics and Gynecology. ,vol. 97, pp. 283- 293 ,(1967) , 10.1016/0002-9378(67)90488-7
Joseph E. Sokal, EFFECTS OF CANCER CHEMOTHERAPEUTIC AGENTS ON THE HUMAN FETUS Journal of the American Medical Association. ,vol. 172, pp. 1765- 1771 ,(1960) , 10.1001/JAMA.1960.63020160002008
J. G. Dumoulin, K. D. Bagshawe, PREGNANCY FOLLOWING CHORIOCARCINOMA BJOG: An International Journal of Obstetrics and Gynaecology. ,vol. 70, pp. 1068- 1072 ,(1963) , 10.1111/J.1471-0528.1963.TB15056.X
Averill A. Liebow, Arthur Steer, James G. Billingsley, Desquamative interstitial pneumonia The American Journal of Medicine. ,vol. 39, pp. 369- 404 ,(1965) , 10.1016/0002-9343(65)90206-8
G. R�hrborn, I. Hansmann, Induced chromosome aberrations in unfertilized oocytes of mice Humangenetik. ,vol. 13, pp. 184- 198 ,(1971) , 10.1007/BF00326941
JOSEF WARKANY, Congenital Malformations in Autosomal Trisomy Syndromes Archives of Pediatrics & Adolescent Medicine. ,vol. 112, pp. 502- 517 ,(1966) , 10.1001/ARCHPEDI.1966.02090150046002
D. H. Van Thiel, G. T. Ross, M. B. Lipsett, Pregnancies after Chemotherapy of Trophoblastic Neoplasms Science. ,vol. 169, pp. 1326- 1327 ,(1970) , 10.1126/SCIENCE.169.3952.1326
C ROBERTS, Where have all the Conceptions Gone The Lancet. ,vol. 305, pp. 498- 499 ,(1975) , 10.1016/S0140-6736(75)92837-8