Germline mutations in the TP53 gene.
作者： Eeles Ra
DOI:
关键词: Mutation 、 Predictive testing 、 Genetics 、 Point mutation 、 Cancer 、 Penetrance 、 Adrenocortical carcinoma 、 Germline mutation 、 Li–Fraumeni syndrome 、 Oncology 、 Biology 、 Internal medicine
摘要: … testing may be desirable in all LFS and LFL families. Individuals carrying TP53 mutations could be offered chemoprevention within trials in an effort to reduce their mortality from cancer. …
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