作者: Risto O. Roine , Perttu J. Lindsberg
关键词: Insulin 、 Surgery 、 Therapeutic effect 、 Cardiology 、 Internal medicine 、 Magnetic resonance imaging 、 Lesion 、 Glucose control 、 Ischemia 、 Medicine 、 Infarction 、 Experimental research
摘要: There is overwhelming evidence that hyperglycemia detrimental in cerebral ischemia, not only from experimental research but also an increasing number of clinical studies.1,2⇓ Elevated admission glucose levels are associated with increased mortality and worse functional outcome ischemic stroke.3,4⇓ In human magnetic resonance imaging studies, tissue at risk will progress to infarction the presence high blood level, diffusion-weighted lesion grow even recanalized patients receiving thrombolytic therapy.5–7⇓⇓ The mechanisms hyperglycemic cellular injury have been largely clarified.8 Although damage made by reduced lowering therapeutic effect rapidly acting insulin still remains be proven trials.8 This article complements original observation published last year same group: deleterious …