Analysis of resting noise characteristics of three EIT systems in order to compare suitability for time difference imaging with scalp electrodes during epileptic seizures

作者: L Fabrizi , A McEwan , E Woo , D S Holder

DOI: 10.1088/0967-3334/28/7/S16

关键词: Epileptic seizureImaging phantomNoiseBiomedical engineeringInput impedanceMaterials scienceHuman headMultiplexerElectrical impedance tomographyResistorBiophysicsPhysiology (medical)Physiology

摘要: Electrical impedance tomography measurements in clinical applications are limited by an undesired noise component. We have investigated the three systems suitable for imaging epileptic seizures, UCH Mark1b, Mark2.5 and KHU Mark1 16 channel, at applied frequencies steps from 1 to 100 kHz, varying load impedance, single terminal or multiplexed measurements, test objects of increasing complexity a resistor saline filled tank human volunteer. The was white, increased about 0.03% rms on 0.08% human; it with but independent use multiplexer. delivered best performance spectra 0.02%, which could be further reduced averaging level where reliable changes 0.1% estimated during seizures appears plausible.

参考文章(28)
RJ Yerworth, RH Bayford, A McEwan, DS Holder, L Horesh, Specification and calibration of a multi-frequency MEIT system for stroke XI Conf. on Biomedical application of EIT, London, UK (2005). ,(2005)
L. Fabrizi, L. Horesh, A. McEwan, D. S. Holde, A feasibility study for imaging of epileptic seizures by EIT using a realistic FEM of the head In: Kim, SI and Suh, TS, (eds.) WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING 2006, VOL 14, PTS 1-6. (pp. 3874 - 3877). SPRINGER-VERLAG BERLIN (2007). pp. 3874- 3877 ,(2007) , 10.1007/978-3-540-36841-0_980
A. Van Harreveld, J.P. Schadé, Changes in the electrical conductivity of cerebral cortex during seizure activity. Experimental Neurology. ,vol. 5, pp. 383- 400 ,(1962) , 10.1016/0014-4886(62)90051-1
A Romsauerova, A McEwan, D S Holder, Identification of a suitable current waveform for acute stroke imaging Physiological Measurement. ,vol. 27, ,(2006) , 10.1088/0967-3334/27/5/S18
A Tizzard, L Horesh, R J Yerworth, D S Holder, R H Bayford, Generating accurate finite element meshes for the forward model of the human head in EIT. Physiological Measurement. ,vol. 26, ,(2005) , 10.1088/0967-3334/26/2/024
A J Wilson, P Milnes, A R Waterworth, R H Smallwood, B H Brown, Mk3.5: a modular, multi-frequency successor to the Mk3a EIS/EIT system. Physiological Measurement. ,vol. 22, pp. 49- 54 ,(2001) , 10.1088/0967-3334/22/1/307
I. D. Schneider, R. Kleffel, D. Jennings, A. J. Courtenay, Design of an electrical impedance tomography phantom using active elements. Medical & Biological Engineering & Computing. ,vol. 38, pp. 390- 394 ,(2000) , 10.1007/BF02345007
R J Yerworth, R H Bayford, G Cusick, M Conway, D S Holder, Design and performance of the UCLH mark 1b 64 channel electrical impedance tomography (EIT) system, optimized for imaging brain function. Physiological Measurement. ,vol. 23, pp. 149- 158 ,(2002) , 10.1088/0967-3334/23/1/314
W. R. Bennett, Spectra of quantized signals Bell System Technical Journal. ,vol. 27, pp. 446- 472 ,(1948) , 10.1002/J.1538-7305.1948.TB01340.X