Leptin and the Gastrointestinal Tract
作者： SANDRA GUILMEAU , ROBERT DUCROC , ANDRÉ BADO
DOI: 10.1016/B978-012369442-3/50150-1
关键词: Lumen (anatomy) 、 Internal medicine 、 Stomach 、 Gastrointestinal tract 、 Secretion 、 Endocrinology 、 Leptin 、 Biology 、 Pathophysiology 、 Nutrient absorption
摘要: ABSTRACT The initial view that leptin, a 16-kDa protein-encoded by the ob gene, is an adipocyte-derived signal, has been modified identification of other producing tissues, such as stomach. discovery stomach-derived mainly secreted in lumen, initiated several investigations leading to suggested clues: (1) gut leptin may act locally within gastrointestinal tract regulate intestinal functions nutrient absorption, (2) integrate meal-related signals from and thus participate short-term regulation energy balance, (3) secretion have pathophysiological implications.
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