Prognostic factors for surgery of neocortical temporal lobe epilepsy
作者： J. Janszky , H.W. Pannek , A. Fogarasi , B. Bone , R. Schulz
DOI: 10.1016/J.SEIZURE.2005.12.002
关键词: Temporal lobe 、 Psychology 、 Cortical dysplasia 、 Ictal 、 Epilepsy 、 Electroencephalography 、 Benign tumor 、 Surgery 、 Preoperative care 、 Postoperative outcome 、 Neurology 、 Clinical neurology 、 General Medicine
摘要: Summary Objectives In the current classification of epilepsies two forms temporal lobe epilepsy (TLE) were included: mesial and lateral (neocortical) TLE. We aimed at identifying prognostic factors for surgical outcome lesional neocortical Methods included consecutive patients who had undergone presurgical evaluation including ictal video-EEG high-resolution MRI, TLE due to epileptogenic lesions, a lesionectomy >2-year follow-up. Results There 29 met inclusion criteria. Twenty them became postoperatively seizure-free. Patients' mean age was 34.8±9 years (range 18–52). The onset 20.1±8 years. found that left-sided surgery ( p =0.048) focal cortical dysplasia (FCD) on MRI =0.005) associated with non-seizure-free outcome, while lateralized/localized EEG seizure pattern =0.032), tumors =0.013), favorable situation 6-month postoperative 2-year seizure-freedom Conclusion More than two-thirds seizure-free postoperatively. Lateralized/localized seizure-freedom, FCD poor outcome. is reliable predictor long-term
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