Clinical issues in renal transplantation in the elderly

摘要: Kidney transplantation is the best renal replacement therapy option and superior to dialysis in elderly end-stage disease (ESRD) patients. Furthermore, outcome of comparable younger patients terms allograft survival. The exact nature this phenomenon not completely clear. As population continues grow, it becomes more important identify specific issues associated with kidney transplantation. In particular, transplant recipients might have a lower chance acute rejection as their immune systems seem be less reactive. This predispose greater risk post-transplant infectious complications or malignancies. due differences pharmacokinetics, require doses immunosuppressive medication. main cause graft failure death functioning also considering scarcity donor organs, make sense recommend transplanting extended criteria kidneys. approach would balance shorter patient survival compared recipients. conclusion, old age should preclude ESRD from However, that do immunosuppression other aspects managing considered.