A murine monoclonal antibody directed against a yeast cell wall glycoprotein antigen of the yeast genus Saccharomyces

作者: Michael Bröker , Hans-Peter Harthus , Roger M.R. Barnes

DOI: 10.1111/J.1574-6968.1994.TB06844.X

关键词: YeastGlycoproteinSaccharomycesBiologySaccharomyces cerevisiaeImmunofluorescenceMolecular biologyBiochemistryEpitopeAntigenicityMonoclonal antibody

摘要: Murine monoclonal antibodies (mAbs) were selected against a cell wall glycoprotein of Saccharomyces cerevisiae. One the mAbs (92-276/018) specifically identified S. cerevisiae and sibling species paradoxus, pastorianus bayanus in immunofluorescence studies immunoblot analyses, while no other yeast genera except recognized. Further analysis indicated that mAb 92-276/018 reacts with an epitope carbohydrate chain glycoproteins.

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