Genetics of Atrial Septal Defect
作者： Andrés Sánchez Cascos
关键词: Dermatoglyphics 、 Ostium Primum Defect 、 Turner syndrome 、 Trisomy 、 Anatomy 、 Medicine 、 Down syndrome 、 Polydactyly 、 Tracheoesophageal fistula 、 Fistula
摘要: Of 109 cases of atrial septal defect, with an isolated defect (92 cases) showed a female preponderance (sex ratio 0·64), but there was higher risk to the sibs male patients, suggesting multifactorial mechanism. Dermatoglyphs large number whorls on fingers. In 17 were multiple malformations, such as Holt-Oram syndrome (hypoplastic and triphalangic thumb, ostium secundum defect), polydactyly plus primum tracheo-oesophageal fistula.
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