An RNAi screen identifies KIF15 as a novel regulator of the endocytic trafficking of integrin

作者: A. Eskova , B. Knapp , D. Matelska , S. Reusing , A. Arjonen

DOI: 10.1242/JCS.137281

关键词: IntegrinCancer researchClathrinInternalizationCollagen receptorEndocytic cycleCD49cIntegrin alpha MIntegrin, beta 6BiologyCell biology

摘要: … (ARF1 and NF2) did not alter the expression levels of α2 integrin, suggesting a role for these proteins in α2 integrin … Potentially, ARF1 inhibits α2 integrin trafficking by regulating its …

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