Stimulation-dependent recycling of integrin beta1 regulated by ARF6 and Rab11.
作者： Aimee M. Powelka , Jianlan Sun , Jian Li , Minggeng Gao , Leslie M. Shaw
DOI: 10.1111/J.1600-0854.2004.00150.X
关键词:
摘要: In comparison to the internalization pathways of endocytosis, recycling are less understood. Even defined is process regulated recycling, as few examples exist and their underlying mechanisms remain be clarified. this study, we examine endocytic integrin beta1, a that has been suggested play an important role during cell motility by mediating redistribution integrins migrating front. External stimulation regulates itinerary mainly at internal compartment likely subset endosomes. This stimulation-dependent ARF6 Rab11, also requires actin cytoskeleton in ARF6-dependent manner. Consistent with these observations being relevant for motility, mutant forms affect either rearrangement or inhibit breast cancer line.
sci-hub.se 参考文章(71)
Marino Zerial, Heidi McBride, Rab proteins as membrane organizers Nature Reviews Molecular Cell Biology. ,vol. 2, pp. 107- 117 ,(2001) , 10.1038/35052055
F.A. Blumenstock, T.M. Curtis, B. Gao, T.M. Saba, F.L. Minnear, Increased recycling of (alpha)5(beta)1 integrins by lung endothelial cells in response to tumor necrosis factor. Journal of Cell Science. ,vol. 113, pp. 247- 257 ,(2000)
J. Ivaska, PKCepsilon controls the traffic of beta1 integrins in motile cells The EMBO Journal. ,vol. 21, pp. 3608- 3619 ,(2002) , 10.1093/EMBOJ/CDF371
Takao Sakai, Qinghong Zhang, Reinhard Fässler, Deane F. Mosher, Modulation of β1A Integrin Functions by Tyrosine Residues in the β1 Cytoplasmic Domain Journal of Cell Biology. ,vol. 141, pp. 527- 538 ,(1998) , 10.1083/JCB.141.2.527
H. Riezman, M.I. Geli, Endocytic internalization in yeast and animal cells: similar and different. Journal of Cell Science. ,vol. 111, pp. 1031- 1037 ,(1998)
Keith E. Mostov, Michael H. Cardone, Regulation of protein traffic in polarized epithelial cells BioEssays. ,vol. 17, pp. 129- 138 ,(1995) , 10.1002/BIES.950170208
Moira A. Lawson, Frederick R. Maxfield, Ca 2+ - and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils Nature. ,vol. 377, pp. 75- 79 ,(1995) , 10.1038/377075A0
Felipe Palacios, Leo Price, Jill Schweitzer, John G Collard, Crislyn D'Souza‐Schorey, An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration The EMBO Journal. ,vol. 20, pp. 4973- 4986 ,(2001) , 10.1093/EMBOJ/20.17.4973
Karl Matter, Ira Mellman, MECHANISMS OF CELL POLARITY : SORTING AND TRANSPORT IN EPITHELIAL CELLS Current Opinion in Cell Biology. ,vol. 6, pp. 545- 554 ,(1994) , 10.1016/0955-0674(94)90075-2
Steve Caplan, Naava Naslavsky, Lisa M Hartnell, Robert Lodge, Roman S Polishchuk, Julie G Donaldson, Juan S Bonifacino, A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane The EMBO Journal. ,vol. 21, pp. 2557- 2567 ,(2002) , 10.1093/EMBOJ/21.11.2557