Magnetic resonance imaging using paramagnetic contrast agents in the clinical evaluation of myocardial infarction

摘要: Magnetic resonance imaging (MRI) is a noninvasive and specific method for production of high resolution tomographic images in blocks three-dimensional information. Apart from scintigraphic techniques computed tomography the evaluation myocardial ischemia infarcts, MRI has emerged as new diagnostic technique to study extent anatomical functional abnormalities patients with coronary artery disease. Conventional noncontrast can identify acutely infarcted areas, although difficulty identifying infarcts suggests potential role contrast enhanced MRI. The use paramagnetic agent gadolinium (Gd)-diethylene triamine pentaacetic acid (DTPA) improves depiction myocardium on Tl-weighted spin-echo MR that are obtained soon after acute infarction. This particular interest estimation infarct size. Furthermore, ultrafast subsecond imaging, combination Gd-DTPA, offers analyze cardiac first pass perfusion. development nontoxic agents which selectively taken up by viable would be helpful assessing presence ischemic/infarcted salvage following reperfusion.