Excitation-Contraction Coupling in Cardiac Muscle

作者: A. W. Trafford , D. A. Eisner

DOI: 10.1007/978-94-015-9926-9_2

关键词: Excitation–contraction couplingCalciumContractile proteinSurface membraneCardiac electrophysiologyNeuroscienceCardiac muscleContraction (grammar)PhysicsPharmacological modulation

摘要: Excitation-contraction coupling concerns the processes linking electrical excitation of surface membrane to contraction. As shown in Fig. 1 A, action potential produces a systolic increase calcium that then activates This chapter will focus on control and largely ignore contractile protein mechanisms follow Ca. These events are described detail other chapters. Equally, grounds space, we whole field pharmacological modulation e-c coupling. The reader is directed following books for recent summaries broad cardiac electrophysiology contraction (Bers, 2001;Zipes & Jalife, 2000;Sperelakis et al., 2001). An overview cellular Ca handling 1A.

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