BENZENESULPHONAMIDE COMPOUNDS APPLICABLE FOR TREATING DISORDERS RESPONSIVE TO DOPAMINE DRECEPTOR MODULATION

作者: Unger Liliane , Bespalov Anton , Lange Udo , Dresher Karla , Jongen-Relo Ana Ljusija

DOI:

关键词: Combinatorial chemistryChemistryDopamineSelectivity

摘要: FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to compounds of formula Iwherein Ris specified in a group consisting hydrogen and linear C-Calkyl; Rrepresents or methyl; hydrogen, C-C-alkyl C-C-alkoxy, C-C-alkyl; n represents 0, 1 2; physiologically stable salts these compounds. The also pharmaceutical composition containing at least one compound (I) possessing dopamine Dreceptor activity selectivity the use I for treating disorders responsive effect antagonists, further method antagonists Dagonists that involves administering an effective amount acid addition salt individual need thereof.EFFECT: there are prepared described new which can find application diseases nervous system.27 cl, 18 ex, tbl

参考文章(2)
Andreas Haupt, Herve Geneste, Liliane Unger, Wilfried Braje, Karla Drescher, Roland Grandel, Sean Colm Turner, Wilfried Lubisch, Daryl R. Sauer, N-[(piperazinyl)hetaryl]arylsulfonamide compounds with affinity for the dopamine d3 receptor ,(2004)