Composition and lipid formulation of a hyaluronan-degrading enzyme and the use thereof for treatment of benign prostatic hyperplasia

作者: Louis Howard Bookbinder , Gregory Ian Frost , Curtis Thompson , Xiaoming Li , Mysore Ramprasad

DOI:

关键词: EnzymeHyperplasiaPharmacologyReductaseComposition (combinatorics)Chemistry

摘要: Provided are compositions and formulations or co-formulations containing a hyaluronan degrading enzyme. The compositions, can also contain another therapeutic agent, such as one that is suitable for treatment of Benign Prostatic Hyperplasia, example, 5-alpha reductase inhibitor. be used the Hyperplasia. provided in combinations with more other agents

参考文章(285)
A. Lesk, Computational molecular biology Oxford University Press, Inc.. ,(1988)
Zaki Megeed, Joseph Cappello, Hamidreza Ghandehari, Controlled release of plasmid DNA from a genetically engineered silk-elastinlike hydrogel. Pharmaceutical Research. ,vol. 19, pp. 954- 959 ,(2002) , 10.1023/A:1016406120288
Michael A. Muskat, Joe W. Pita, Scott Mershon, Chemiluminescent reactive vessel ,(1992)
Xuan Cheng, Xin Ming, Maria A. Croyle, PEGylated adenoviruses for gene delivery to the intestinal epithelium by the oral route. Pharmaceutical Research. ,vol. 20, pp. 1444- 1451 ,(2003) , 10.1023/A:1025714412337
Glenn J. Gormley, Elizabeth Stoner, Reginald C. Bruskewitz, Julianne Imperato-McGinley, Patrick C. Walsh, John D. McConnell, Gerald L. Andriole, Jack Geller, Bruce R. Bracken, Joyce S. Tenover, E. Darracott Vaughan, Frances Pappas, Alice Taylor, Bruce Binkowitz, Jennifer Ng, The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group. The New England Journal of Medicine. ,vol. 327, pp. 1185- 1191 ,(1992) , 10.1056/NEJM199210223271701
H. Hartounian, C. Pepper, M. Patel, CGMP MANUFACTURING SCALE-UP OF A MULTIVESICULAR LIPID BASED DRUG DELIVERY SYSTEM Pharmaceutical engineering. ,vol. 19, ,(1999)
Hugh G. Griffin, Annette M. Griffin, Computer analysis of sequence data. Methods of Molecular Biology. ,vol. 24, pp. 1- 8 ,(1994) , 10.1385/0-89603-246-9:1
Charles William Lamden, The Securities and Exchange Commission ,(1978)