Apoptosis and Cancer
作者： Mei Lan Tan , Heng Kean Tan , Tengku Sifzizul Tengku Muhammad
DOI: 10.1007/978-3-662-44006-3_13
关键词: Necroptosis 、 UVB-induced apoptosis 、 Disease 、 Proteasome inhibitor 、 Cancer 、 Apoptosis 、 Cancer research 、 Medicine 、 Programmed cell death 、 Autophagy
摘要: Cancer is a worldwide endemic and continues to be one of the most difficult diseases treat manage, which may due multifactorial nature disease. generally exhibits considerable genetic complexity aberrant cell death survival signaling pathways. Resistance induction has long been recognized as hallmark cancer. Therefore, increased understanding underlying molecular events regulating different mechanisms such apoptosis, necroptosis, autophagy provided new possibilities for targeted interference these This chapter highlights significant pathways apoptosis relevant therapeutic targets summarizes current state development specific modulators overall outcome this group novel therapeutics in various phases clinical trials.
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