Inhibitors of biotin protein ligase
作者： Cvetan Stojkoski , Steven William Polyak , Grant William Booker , John Campbell Wallace
DOI:
关键词: Substrate (chemistry) 、 Biotinylation 、 Biochemistry 、 DNA ligase 、 Biotin 、 Chemistry
摘要: The present invention relates to a method for identifying an inhibitor of biotin protein ligase. include the steps (a) providing substrate, wherein substrate may be biotinylated; (b) contacting with and ligase in presence test compound; (c) determining extent biotinylation by (d) compound as reduction compared absence compound.
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