Loss of Mhc and Neutral Variation in Peary Caribou: Genetic Drift Is Not Mitigated by Balancing Selection or Exacerbated by Mhc Allele Distributions

摘要: Theory and empirical results suggest that the rate of loss variation at Mhc neutral microsatellite loci may differ because selection influences genes, a high proportion rare alleles result in rates via drift. Most published studies compare various contemporary populations to infer effects population size on genetic variation, even though different are likely have demographic histories also affect variation. We directly compared Peary caribou by comparing historical samples. observed similar proportions were lost over time each type marker despite strong evidence for genes. These microsatellites can be used estimate genome-wide levels but adaptive potential is following bottlenecks. However, gene conversion recombination act increase