Surface activation of blood coagulation, fibrinolysis and kinin formation.
作者： Ronald L. Heimark , Kotoku Kurachi , Kazuo Fujikawa , Earl W. Davie
DOI: 10.1038/286456A0
关键词: Kinin 、 Kallikrein 、 Prekallikrein 、 Chemistry 、 Factor XII 、 High-molecular-weight kininogen 、 Endocrinology 、 Internal medicine 、 Plasmin 、 Fibrinolysis 、 Coagulation
摘要: The activation of plasma prekallikrein by single-chain factor XII has been studied in the presence high molecular weight kininogen and kaolin. data indicate that can initiate blood coagulation, fibrinolysis or kinin generation kaolin does so converting to kallikrein. An enzyme cascade is then generated leading formation fibrin, plasmin bradykinin three closely related physiological events.
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