作者: Philip S. Hartman , Robert K. Herman
DOI: 10.1007/BF00384393
关键词: Embryo 、 Mutation 、 Somatic cell 、 X chromosome 、 Genetics 、 Molecular biology 、 Larva 、 Radiosensitivity 、 Biology 、 Cell 、 Transformation (genetics)
摘要: Wild-type male embryos and young larvae of the nematode Caenorhabditis elegans were more sensitive than wild-type hermaphrodites to inactivation by gamma rays; males have one X chromosome per cell (XO), whereas two (XX). Furthermore, after transformation into fertile a her-1 mutation, XO animals radiosensitive XX animals; transformed tra-1 mutation did not show increased radiosensitivity. It is concluded that are because they rather two, predominant mode involves damage single chromosome. No sex-specific differences in survival observed UV irradiation.