Effects of chronic gamma irradiation: a multigenerational study using Caenorhabditis elegans.
作者： Adeline Buisset-Goussen , Benoit Goussen , Claire Della-Vedova , Simon Galas , Christelle Adam-Guillermin
DOI: 10.1016/J.JENVRAD.2014.07.014
关键词:
摘要: Abstract The effects of chronic exposure to 137 Cs gamma radiation (dose rate ranging from 6.6 42.7 mGy h −1 ) on growth and reproductive ability were carried out over three generations Caenorhabditis elegans (F0, F1, F2). Exposure began at the egg stage for first generation was stopped end laying third-generation eggs (F2). At same time, two subsequent parental returned control conditions (F1’ F2’). There no radiation-induced significant effect growth, hatchability, cumulative number larvae within generations. Moreover, differences found in parameters (hatching length, maximal a constant related rate) among However, decrease across exposed observed between F0 F2 highest dose (238.8 ± 15.4 171.2 ± 13.1 per individual, respectively). Besides, F1′ lay significantly fewer than F1 tested rates 6.6, 8.1, 19.4, 28.1 mGy h . Our results confirmed that reproduction (here, larvae) is most sensitive endpoint affected by ionizing radiation. obtained revealed transgenerational second generation, non-exposed indeed more generation.
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