Consequences of a multi-generation exposure to uranium on Caenorhabditis elegans life parameters and sensitivity.

摘要: The assessment of toxic effects at biologically and ecologically relevant scales is an important challenge in ecosystem protection. Indeed, stressors may impact populations much longer term than the usual timescale toxicity tests. It therefore to study evolutionary response a population under chronic stress. We performed 16-generation assess evolution two ubiquitous nematode Caenorhabditis elegans control conditions or exposed 1.1 mM uranium. Several generations were selected growth, reproduction, survival, dose-responses relationships, through exposure range concentrations (from 0 1.2 mM U) with all endpoints measured daily. Our experiment showed adaptation individuals experimental (increase maximal length decrease fecundity) for both populations. also observed increase adverse (reduction growth fertility) as function uranium concentration. pointed out emergence differentiation reproduction traits. In contrast, no was on results confirm importance assessing environmental risk related pollutant multi-generational studies.