作者: H. Ichikawa , H.W. Jin , S. Terayama , T. Yamaai , S. Matsuo
DOI: 10.1016/J.BRAINRES.2007.03.060
关键词: Proprioception 、 Masseteric nerve 、 Central nervous system 、 Nervous system 、 Anatomy 、 Neurotrophic factors 、 Brain-derived neurotrophic factor 、 Axotomy 、 Sensory receptor 、 Medicine
摘要: Abstract The effect of neonatal masseteric nerve transection on primary proprioceptors was examined in the mesencephalic trigeminal tract nucleus (Mes5) rat. At 72 h to 21 days after injury, number Mes5 neurons decreased side ipsilateral transection. means ± SD percentage proportion ipsilateral/contralateral at and were 69.9 ± 7.5% 58.2 ± 14.6%, respectively. application brain-derived neurotrophic factor proximal stump delayed loss injury; mean numbers ± SD contralateral injured animals with BDNF 553.6 ± 61.9 558.4 ± 55.3, Saline had no injury-induced neurons; i.e., 367.3 ± 72.5 543 ± 33.5, These findings indicate that are sensitive injury. survival during early postnatal period is probably dependent upon nervous system.