Oxidatively generated complex DNA damage: tandem and clustered lesions.

作者: Jean Cadet , Jean-Luc Ravanat , Marisa TavernaPorro , Hervé Menoni , Dimitar Angelov

DOI: 10.1016/J.CANLET.2012.04.005

关键词: BiochemistryDNADNA repairPurineMutagenesisNucleobaseHydroxyl radicalChemistryDNA damageOxidative stress

摘要: … Recombination of the two later species give rise to peroxynitrite anion (ONOO - ) that is converted upon reaction with CO 2 into nitrosoperoxycarbonate, the precursor of carbonate anion …

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