Recent progress of antibacterial natural products: Future antibiotics candidates
作者： Jiangkun Dai , Rui Han , Yujie Xu , Na Li , Junru Wang
DOI: 10.1016/J.BIOORG.2020.103922
关键词: Lead (geology) 、 Research based 、 Chemistry 、 Drug discovery 、 Antibiotics 、 Biochemical engineering 、 Natural (archaeology) 、 Organic chemistry 、 Biochemistry 、 Molecular biology
摘要: Abstract The discovery of novel antibacterial molecules plays a key role in solving the current antibiotic crisis issue. Natural products have long been an important source drug discovery. Herein, we reviewed 256 natural from 11 structural classes period 2016–01/2020, which were selected by SciFinder with new compounds or structures and MICs lower than 10 μg/mL 10 μM as criterions. This review will provide some effective lead for medicinal chemists, promote antibiotics research based on to next level.
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