Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors
作者： Mark S Kramer , Neal Cutler , John Feighner , Ram Shrivastava , John Carman
DOI: 10.1126/SCIENCE.281.5383.1640
关键词: Monoaminergic 、 Mechanism (biology) 、 Internal medicine 、 Endocrinology 、 Antidepressant 、 Receptor 、 Blockade 、 Monoamine neurotransmitter 、 Medicine 、 Substance P 、 NK1 receptor antagonist
摘要: … in many patients, and the potentially distressing adverse effects of … Efficacy measurements were made at the end of weeks 1, 2, … We conclude that psychological stress causes release of …
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