Gemcitabine and vinorelbine as a salvage regimen for relapse in Hodgkin lymphoma after autologous hematopoietic stem cell transplantation.

作者: M. Fevzi Ozkaynak , Somasundaram Jayabose

DOI: 10.1080/08880010490272975

关键词: Internal medicineOncologyHodgkin lymphomaSalvage regimenMedicineGemcitabineVinorelbineHematopoietic stem cell transplantation

摘要: The authors describe two consecutive pediatric patients with relapsed Hodgkin lymphoma after autologous hematopoietic stem cell transplantation who had objective responses a novel combination of gemcitabine and vinorelbine. This promising needs to be studied in larger number disease patients.

参考文章(14)
Orhan Sezer, Jan Eucker, Christian Jakob, Olaf Kaufmann, Peter Schmid, Kurt Possinger, Achievement of complete remission in refractory Hodgkin's disease with prolonged infusion of gemcitabine. Investigational New Drugs. ,vol. 19, pp. 101- 104 ,(2001) , 10.1023/A:1006478702342
David G. Poplack, Philip A. Pizzo, Principles and Practice of Pediatric Oncology ,(1989)
A P Rapoport, J M Rowe, P A Kouides, R A Duerst, C N Abboud, J L Liesveld, C H Packman, S Eberly, M Sherman, M A Tanner, One hundred autotransplants for relapsed or refractory Hodgkin's disease and lymphoma: value of pretransplant disease status for predicting outcome. Journal of Clinical Oncology. ,vol. 11, pp. 2351- 2361 ,(1993) , 10.1200/JCO.1993.11.12.2351
A. Santoro, H. Bredenfeld, L. Devizzi, H. Tesch, V. Bonfante, S. Viviani, F. Fiedler, H. Soto Parra, C. Benoehr, M. Pacini, G. Bonadonna, V. Diehl, Gemcitabine in the Treatment of Refractory Hodgkin’s Disease: Results of a Multicenter Phase II Study Journal of Clinical Oncology. ,vol. 18, pp. 2615- 2619 ,(2000) , 10.1200/JCO.2000.18.13.2615
E Laack, T Mende, J Benk, A Chemaissani, J Scholtze, C Lorenz, A Niestroy, K Dalhoff, T Müller, T Walter, H Dürk, L Edler, D.K Hossfeld, Gemcitabine and vinorelbine as first-line chemotherapy for advanced non-small cell lung cancer: a phase II trial. European Journal of Cancer. ,vol. 37, pp. 583- 590 ,(2001) , 10.1016/S0959-8049(00)00441-X
S. Rule, M. Tighe, S. Davies, S. Johnson, Vinorelbine in the treatment of lymphoma. Hematological Oncology. ,vol. 16, pp. 101- 105 ,(1998) , 10.1002/(SICI)1099-1069(199809)16:3<101::AID-HON629>3.0.CO;2-#
Bonfante, Viviani, Santoro, Devizzi, Di Russo, Zanini, Soncini, Soto Parra, Valagussa, Bonadonna, Ifosfamide and vinorelbine: an active regimen for patients with relapsed or refractory Hodgkin's disease. British Journal of Haematology. ,vol. 103, pp. 533- 535 ,(1998) , 10.1046/J.1365-2141.1998.00989.X
PL Zinzani, V Stefoni, M Tani, PP Piccaluga, F Gherlinzoni, P Albertini, M Bendandi, S Tura, Value of gemcitabine treatment in heavily pretreated Hodgkin's disease patients. Haematologica. ,vol. 85, pp. 926- 929 ,(2000) , 10.3324/%X
D.G. Savage, S.A. I Rule, M. Tighe, T.J. Garrett, W.M. Oster, R.T. Lee, J. Ruiz, D. Heitjan, M.L. Keohan, M. Flamm, S.A. Johnson, Gemcitabine for relapsed or resistant lymphoma Annals of Oncology. ,vol. 11, pp. 595- 597 ,(2000) , 10.1023/A:1008307528519