Disorders of Protein Metabolism

摘要: This chapter discusses the disorders of protein metabolism. Amyloidosis is a generic term for group clinically and biochemically diverse diseases characterized by deposition an insoluble fibrillary in extracellular space. Over 16 distinct amyloids are known. Amyloids categorized on basis their chemical structure. Cerebral amyloid deposits can be divided into several groups based constitution: b/A4 amyloid, cystatin C proteinase-resistant amyloid. Amyloid demonstrated its strong reaction with iodine sulfuric acid. The specific conformation fibrils always same, irrespective nature protein. Other metabolism include lipid proteinosis, which rare hereditary disorder skin mucous membranes monoclonal gammopathies that includes benign malignant conditions increased levels immunoglobulin.