On the Equivalence between the Sigmoidal Approach and Utkin's Approach for Piecewise-Linear Models of Gene Regulatory Networks

作者: Nicoletta Del Buono , Cinzia Elia , Luciano Lopez

DOI: 10.1137/130950483

关键词: Dynamical systems theoryVector fieldDiscontinuity (linguistics)Dynamical systemPiecewiseApplied mathematicsMathematicsEquivalence (measure theory)HyperplaneMathematical analysisIntersection

摘要: This paper is concerned with piecewise-linear dynamical systems modeling a simple class of gene regulatory networks. One the main issues when dealing these problems that vector field not defined on discontinuity hyperplanes. Two different methods are usually employed in literature to overcome this issue: Filippov's convexification approach and steep sigmoidal approach. A particular selection field, namely Utkin's will be interest us. Our purpose twofold: show well intersection $\Sigma$ two hyperplanes (under assumptions attractivity) prove that, for nodally attractive three surfaces, equivalent, i.e., corresponding solutions same. allows us study piecewise system, hence network it models, no ambiguity.

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